Group Leader Pharmacology and Screening Oncology

Switzerland
Posted 4 months ago

Key responsibilities

  • Establish well-defined and ambitious objectives, as well as clear responsibilities and processes for monitoring work, assessing results, and recognizing achievements
  • Drive engagement by empowering your team, creating a feeling of belonging, fostering open dialogue, and sharing ownership and visibility
  • Develop your team through individual development plans, ongoing feedbacks & coaching
  • Develop, manage and report on the functional team activities defined in the Translational Medicine Development plan, and deliver P&S data packages generated by external vendors:
    • In vitro/in vivo pharmacology compounds selection and profiling, including off-target characterization
    • Proof of concept in vivo studies – PK/PD
    • Mechanism of action studies
  • Represent the Pharmacology and Screening and Translational Medicine function in global core project teams and contribute to the elaboration of the drug development strategy
  • Determine, implement and manage the clinical pharmacodynamic biomarkers analyses, data analyses and reporting according to GCPs and GCLPs and you represent Pharmacology and Screening function in clinical study teams
  • Participate in the preparation of investigator drug brochure, informed consent forms, lab manual and clinical protocol, and report
  • Identify the intellectual property, inventions and innovation opportunities, and collaborate with legal department to feed DPI’s patent portfolio
  • Prepare the pharmacology documentation (summaries for IND and IMPD, briefing documentation for health authorities)
  • Participate in external scientific communications (publications, poster and oral presentations, and press releases)
  • Participate in due diligences and contribute to in/out licensing activities as subject matter expert

Your profile

  • PhD in the field of biomedical research biomedical engineering or equivalent
  • Strong experience in translational pharmacology (including expertise both in preclinical and clinical development) at least 10+ in pharma or biotech
  • First proven experience in working in drug development in oncology
  • Knowledge of GCP and ICH guidelines; animal welfare regulations, and relevant regulatory guidelines
  • First experience in leading and developing further your team and contributing to the department strategy
  • You are used in working in cross-functional team and fast-paced environment, and in leading your teams to achieve the milestones and objectives
  • Excellent communication skills (oral and written) in English
  • You are solution-oriented, resilient to push forward the R&D projects and look to work on complex and innovative compounds, willing to keep hands activities on assigned projects
  • You have excellent command in data analysis and visualization tools and are IT-sounded

Job Features

Job CategoryLIFE SCIENCES

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